Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652013 | 0.98 | KMT2A (0.40) | KMT2APDE7ARAB9ANPC1POLB | |
| SCHEMBL3176738 | 0.88 | PDE7A (0.35) | KMT2APDE7ARAB9ANPC1POLB | |
| SCHEMBL2889210 | 0.88 | KMT2A (0.41) | KMT2APDE7ARAB9ANPC1POLB | |
| SCHEMBL6762179 | 0.87 | HPGD (0.30) | — | |
| SCHEMBL7619891 | 0.87 | THRB (0.39) | PDE7AMAPTSMN1; SMN2LMNACRBN | |
| SCHEMBL12496896 | 0.87 | PDE7A (0.40) | KMT2APDE7ARAB9APOLBMAPT | |
| SCHEMBL7647437 | 0.86 | KMT2A (0.32) | KMT2APDE7ARAB9ANPC1 | |
| SCHEMBL7612862 | 0.85 | CA12 (0.34) | KMT2APDE7A | |
| SCHEMBL1475886 | 0.84 | KMT2A (0.37) | KMT2APDE7ARAB9ANPC1POLB | |
| SCHEMBL2434247 | 0.84 | PDE7A (0.33) | KMT2APDE7ARAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0521334-B1 | Substituted 1-H-3-aryl-pyrrolidin-2,4-dione derivatives, their preparation and their use as insecticides, acaricides and herbicides | BAYER AG (DE) | 1998-09-09 | — | — | EP | disclosed |
| US-5616536-A | INSECTICIDES, MITICIDES, HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |
| US-5589469-A | INSECTICIDES, MITICIDES OR HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-31 | — | — | US | disclosed |
| EP-0521334-A1 | Substituted 1-H-3-aryl-pyrrolidin-2,4-dione derivatives | BAYER AG (DE) | 1993-01-07 | — | — | EP | disclosed |