SCHEMBL6995491

SCHEMBL6995491

CCCc1c(-c2c(F)cccc2Cl)c(Cl)nc2ncnn12

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
ENPP1 P22413 3/20 0.37
KMT2A Q03164 2/20 0.37
TSHR P16473 2/20 0.37
POLB P06746 1/20 0.37
PDE2A O00408 2/20 0.35
MEN1 O00255 1/20 0.35
MAPK1 P28482 1/20 0.35
MBOAT4 Q96T53 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6997181 0.93 ALDH1A1 (0.38) ALDH1A1ENPP1KMT2ATSHRPOLB
SCHEMBL4814229 0.92 ALDH1A1 (0.38) ALDH1A1ENPP1KMT2ATSHRPOLB
SCHEMBL4817006 0.91 ALDH1A1 (0.37) ALDH1A1ENPP1KMT2ATSHRPOLB
SCHEMBL6998016 0.91 ALDH1A1 (0.41) ALDH1A1ENPP1KMT2ATSHRPOLB
SCHEMBL4810488 0.87 ALDH1A1 (0.38) ALDH1A1ENPP1KMT2ATSHRPOLB
SCHEMBL4820443 0.87 ALDH1A1 (0.39) ALDH1A1ENPP1KMT2ATSHRPOLB
SCHEMBL4819336 0.86 MBOAT4 (0.36) ALDH1A1ENPP1KMT2ATSHRPOLB
SCHEMBL4818702 0.86 ALDH1A1 (0.39) ALDH1A1ENPP1KMT2ATSHRPOLB
SCHEMBL4818695 0.85 ALDH1A1 (0.39) ALDH1A1ENPP1KMT2ATSHRPOLB
SCHEMBL4819442 0.85 ALDH1A1 (0.39) ALDH1A1ENPP1KMT2ATSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1054888-B1 FUNGICIDAL 7-ALKYL-TRIAZOLOPYRIMIDINES BASF AG (DE) 2003-11-26 EP claimed
EP-1054888-A1 FUNGICIDAL 7-ALKYL-TRIAZOLOPYRIMIDINES AMERICAN CYANAMID COMPANY (US) 2000-11-29 EP claimed
US-6020338-A Fungicidal 7-alkyl-triazolopyrimidines AMERICAN CYANAMID COMPANY (US) 2000-02-01 US claimed
WO-1999041255-A1 FUNGICIDAL 7-ALKYL-TRIAZOLOPYRIMIDINES AMERICAN CYANAMID COMPANY (US) 1999-08-19 WO claimed