Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 5/20 | 0.56 |
| ▸ | AVPR2 | P30518 | 8/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987427 | 0.91 | AVPR1A (0.59) | AVPR1AAVPR2TP53LMNAAVPR1B | |
| SCHEMBL6991662 | 0.90 | AVPR1A (0.58) | AVPR1AAVPR2TP53LMNAAVPR1B | |
| SCHEMBL6992837 | 0.87 | AVPR2 (0.57) | AVPR1AAVPR2TP53LMNAAVPR1B | |
| SCHEMBL8797156 | 0.87 | AVPR1A (0.73) | AVPR1AAVPR2TP53LMNAAVPR1B | |
| SCHEMBL6989777 | 0.85 | AVPR2 (0.58) | AVPR1AAVPR2TP53LMNAAVPR1B | |
| SCHEMBL6993364 | 0.84 | AVPR1A (0.57) | AVPR1AAVPR2TP53LMNAAVPR1B | |
| SCHEMBL6989072 | 0.82 | AVPR1A (0.55) | AVPR1AAVPR2TP53LMNAAVPR1B | |
| SCHEMBL6990759 | 0.79 | AVPR1A (0.68) | AVPR1AAVPR2AVPR1BMEN1KMT2A | |
| SCHEMBL8820794 | 0.79 | AVPR2 (0.57) | AVPR1AAVPR2TP53NPC1RAB9A | |
| SCHEMBL8796876 | 0.76 | AVPR2 (0.64) | AVPR1AAVPR2TP53LMNAAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |