Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 4/20 | 0.55 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.53 |
| ▸ | PNLIP | P16233 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987427 | 0.84 | AVPR1A (0.59) | AVPR1AAVPR2MEN1KMT2ALMNA | |
| SCHEMBL6991662 | 0.83 | AVPR1A (0.58) | AVPR1AAVPR2LMNATP53AVPR1B | |
| SCHEMBL6993364 | 0.83 | AVPR1A (0.57) | AVPR1AAVPR2MEN1KMT2ALMNA | |
| SCHEMBL6995599 | 0.82 | AVPR1A (0.56) | AVPR1AAVPR2MEN1KMT2ALMNA | |
| SCHEMBL6989777 | 0.82 | AVPR2 (0.58) | AVPR1AAVPR2LMNATP53AVPR1B | |
| SCHEMBL6992837 | 0.82 | AVPR2 (0.57) | AVPR1AAVPR2LMNATP53AVPR1B | |
| SCHEMBL8796903 | 0.77 | AVPR1A (0.74) | AVPR1AAVPR2MEN1KMT2ATP53 | |
| SCHEMBL8316487 | 0.77 | AVPR1A (0.49) | AVPR1AAVPR2PNLIPKCNK3KCNK9 | |
| SCHEMBL6990759 | 0.75 | AVPR1A (0.68) | AVPR1AAVPR2MEN1KMT2AAVPR1B | |
| SCHEMBL6993361 | 0.74 | AVPR2 (0.57) | AVPR1AAVPR2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |