Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 13/20 | 0.57 |
| ▸ | AVPR1A | P37288 | 12/20 | 0.57 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | GLP1R | P43220 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991662 | 0.95 | AVPR1A (0.58) | AVPR2AVPR1AAVPR1BLMNATP53 | |
| SCHEMBL6989777 | 0.92 | AVPR2 (0.58) | AVPR2AVPR1AAVPR1BLMNATP53 | |
| SCHEMBL6987427 | 0.89 | AVPR1A (0.59) | AVPR2AVPR1AAVPR1BLMNATP53 | |
| SCHEMBL6995599 | 0.87 | AVPR1A (0.56) | AVPR2AVPR1AAVPR1BLMNATP53 | |
| SCHEMBL6993364 | 0.85 | AVPR1A (0.57) | AVPR2AVPR1AAVPR1BLMNATP53 | |
| SCHEMBL6989072 | 0.82 | AVPR1A (0.55) | AVPR2AVPR1AAVPR1BLMNATP53 | |
| SCHEMBL6990881 | 0.81 | AVPR2 (0.59) | AVPR2AVPR1AAVPR1BLMNATP53 | |
| SCHEMBL8796809 | 0.80 | AVPR1A (0.79) | AVPR2AVPR1AAVPR1BLMNATP53 | |
| SCHEMBL6993361 | 0.80 | AVPR2 (0.57) | AVPR2AVPR1AAVPR1BLMNATP53 | |
| SCHEMBL5321445 | 0.79 | AVPR1A (0.75) | AVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |