SCHEMBL69957

SCHEMBL69957

COc1ccc(OC)c(O)c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.62
KDM4E B2RXH2 3/20 0.62
MAPK1 P28482 3/20 0.62
HSD17B10 Q99714 3/20 0.62
CYP3A4 P08684 3/20 0.62
ALDH1A1 P00352 2/20 0.62
LMNA P02545 2/20 0.62
HPGD P15428 2/20 0.62
ALOX15 P16050 2/20 0.62
TP53 P04637 2/20 0.62
ALOX12 P18054 1/20 0.62
TDP1 Q9NUW8 2/20 0.52
RECQL P46063 1/20 0.52
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
ERN1 O75460 2/20 0.50
TSHR P16473 1/20 0.50
HIF1A Q16665 1/20 0.50
EPAS1 Q99814 1/20 0.50
MCL1 Q07820 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9742294 0.89 KDM4E (0.65) MAPTKDM4EMAPK1HSD17B10CYP3A4
SCHEMBL11796204 0.87 MAPT (0.50) MAPTKDM4EMAPK1HSD17B10CYP3A4
SCHEMBL69364 0.84 MAPT (0.48) MAPTKDM4EMAPK1HSD17B10CYP3A4
SCHEMBL2588497 0.84 ERN1 (0.60) MAPTKDM4EMAPK1HSD17B10CYP3A4
SCHEMBL25170534 0.84 MAPT (0.48) MAPTKDM4EMAPK1HSD17B10CYP3A4
SCHEMBL9123318 0.83 MAPT (0.52) MAPTKDM4EMAPK1HSD17B10CYP3A4
SCHEMBL1402474 0.83 MAPT (0.61) MAPTKDM4EMAPK1HSD17B10CYP3A4
SCHEMBL28445582 0.83 MAPT (0.46) MAPTKDM4EMAPK1HSD17B10CYP3A4
Syringol SCHEMBL156388 0.81 KDM4E (0.80) MAPTKDM4EMAPK1HSD17B10CYP3A4
SCHEMBL14882573 0.81 MAPT (0.50) MAPTKDM4EMAPK1HSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111171085-A Rhamnose donor protected by orthocarbonate, and preparation method and application thereof 山东大学 2020-05-19 CN claimed
CN-111171085-A Rhamnose donor protected by orthocarbonate, and preparation method and application thereof 山东大学 2020-05-19 CN disclosed
CN-104045809-A Epoxy resin adducts and thermosets thereof DOW GLOBAL TECHNOLOGIES LLC 2014-09-17 CN disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-1006374-B1 Process for producing a resin having a large refractive index MITSUBISHI GAS CHEMICAL CO (JP) 2009-01-07 EP disclosed
US-20050182241-A1 Universal support for nucleic acid synthesis CTGEN, INC. (US) 2005-08-18 US disclosed
US-6534589-B1 Catalytic curing and polymerization of episulfide compound in presence of phenolic compound MITSUBISHI GAS CHEMICAL COMPANY INC. (JP) 2003-03-18 US disclosed
US-6365223-B1 HYDROPHOBIC RESINS CONTAINING SULFUR, SUCH AS POLYTHIOETHERS, DIPPING INTO A LIQUID COMPRISING AN INORGANIC AND/OR AN ORGANIC ACID; THE ORGANIC ACID IS A MIXTURE OF A SULFONIC ACID COMPOUND AND A PHENOL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2002-04-02 US disclosed
EP-1024223-A2 Process for tinting a resin for optical materials MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2000-08-02 EP disclosed
EP-1006374-A2 Process for producing a resin having a large refractive index MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2000-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 MAPT 1923/4885KDM4E 717/4885MAPK1 3382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.