SCHEMBL69364

SCHEMBL69364

COc1ccc(Cl)c(O)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.48
MAPK1 P28482 5/20 0.48
KDM4E B2RXH2 4/20 0.48
HSD17B10 Q99714 3/20 0.48
ALDH1A1 P00352 3/20 0.48
HPGD P15428 3/20 0.48
LMNA P02545 2/20 0.48
CYP3A4 P08684 2/20 0.48
ALOX15 P16050 2/20 0.48
TP53 P04637 2/20 0.48
ALOX12 P18054 2/20 0.48
TDP1 Q9NUW8 2/20 0.43
RECQL P46063 1/20 0.43
ERN1 O75460 3/20 0.41
HIF1A Q16665 1/20 0.41
EPAS1 Q99814 1/20 0.41
MCL1 Q07820 2/20 0.40
RAB9A P51151 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
S1PR4 O95977 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69957 0.84 MAPT (0.62) MAPTMAPK1KDM4EHSD17B10ALDH1A1
SCHEMBL9814072 0.84 CLCN2 (0.41) MAPTMAPK1KDM4EHSD17B10ALDH1A1
SCHEMBL9335491 0.84 MAPK1 (0.46) MAPTMAPK1KDM4EHSD17B10ALDH1A1
SCHEMBL23723768 0.80 ALDH1A1 (0.41) MAPTMAPK1KDM4EHSD17B10ALDH1A1
SCHEMBL4007444 0.79 KDM4E (0.64) MAPTMAPK1KDM4EHSD17B10ALDH1A1
SCHEMBL2935032 0.76 DPP4 (0.52) MAPTMAPK1HSD17B10ALDH1A1HPGD
SCHEMBL9742294 0.75 KDM4E (0.65) MAPTMAPK1KDM4EHSD17B10ALDH1A1
SCHEMBL5469559 0.74 MAPK1 (0.52) MAPTMAPK1KDM4EHSD17B10ALDH1A1
Pentachlorophenol SCHEMBL7590198 0.74 MAPK1 (0.41) MAPTMAPK1KDM4EHSD17B10ALDH1A1
SCHEMBL11796204 0.73 MAPT (0.50) MAPTMAPK1KDM4EHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 MAPT 1923/4885MAPK1 3382/4885KDM4E 717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.