Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 18/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.51 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.51 |
| ▸ | CLK2 | P49760 | 4/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998647 | 0.81 | CLK1 (0.53) | CLK1DYRK1ADYRK1BCLK2PPARA | |
| SCHEMBL1391285 | 0.80 | CLK1 (0.60) | CLK1DYRK1ADYRK1BCLK2PPARA | |
| SCHEMBL6992593 | 0.77 | ICAM1 (0.45) | CLK1 | |
| SCHEMBL2138351 | 0.77 | CLK1 (0.67) | CLK1DYRK1ADYRK1BCLK2CLK4 | |
| SCHEMBL6994746 | 0.76 | TAS1R3 (0.52) | — | |
| SCHEMBL7822377 | 0.74 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL1867721 | 0.72 | CLK1 (0.68) | CLK1DYRK1ADYRK1BCLK2CLK4 | |
| SCHEMBL18003474 | 0.72 | PTPN2 (0.54) | CLK1DYRK1ADYRK1BCLK2PPARA | |
| SCHEMBL19756734 | 0.71 | CLK1 (0.67) | CLK1DYRK1ADYRK1BCLK2CLK4 | |
| SCHEMBL7340422 | 0.71 | CLK1 (0.67) | CLK1DYRK1ADYRK1BCLK2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943618-B1 | 1,2-dioxetane derivative | MATSUMOTO MASAKATSU (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6218135-B1 | EASY TO HANDLE, HEAT STABLE, AND HIGH IN EMISSION EFFICIENCY; FOR IMMUNOASSAYS | Matsumoto, Masakatsu (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0943618-A2 | 1,2-dioxetane derivative | FUJIREBIO INC. (JP) | 1999-09-22 | — | — | EP | disclosed |