Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 11/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 11/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | OXTR | P30559 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995890 | 0.81 | TAS1R3 (0.50) | TAS1R3TAS1R1MAOBMAPTCASP3 | |
| SCHEMBL648621 | 0.79 | MAOB (0.70) | TAS1R3TAS1R1MAOBMAPTCASP3 | |
| SCHEMBL6995985 | 0.76 | CLK1 (0.51) | — | |
| SCHEMBL446971 | 0.76 | TAS1R3 (0.64) | TAS1R3TAS1R1MAPTCASP3SENP7 | |
| SCHEMBL6996968 | 0.75 | POLB (0.44) | TDP1 | |
| SCHEMBL12795529 | 0.73 | TAS1R3 (0.58) | TAS1R3TAS1R1MAPTCASP3SENP7 | |
| SCHEMBL7822377 | 0.73 | SMN1; SMN2 (0.50) | TAS1R3TAS1R1CASP3SENP7 | |
| SCHEMBL31060243 | 0.73 | FLT3 (0.71) | TAS1R3TAS1R1MAPTCASP3SENP7 | |
| SCHEMBL24522315 | 0.72 | TAS1R3 (0.73) | TAS1R3TAS1R1 | |
| SCHEMBL12848552 | 0.72 | TAS1R3 (0.65) | TAS1R3TAS1R1MAOBOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943618-B1 | 1,2-dioxetane derivative | MATSUMOTO MASAKATSU (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6218135-B1 | EASY TO HANDLE, HEAT STABLE, AND HIGH IN EMISSION EFFICIENCY; FOR IMMUNOASSAYS | Matsumoto, Masakatsu (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0943618-A2 | 1,2-dioxetane derivative | FUJIREBIO INC. (JP) | 1999-09-22 | — | — | EP | disclosed |