Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30978820 | 1.00 | TSHR (0.53) | TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1 | |
| SCHEMBL699676 | 1.00 | TSHR (0.53) | TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1 | |
| SCHEMBL29196783 | 0.88 | GPR35 (0.52) | TSHRSMN1; SMN2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL701357 | 0.80 | MEN1 (0.49) | SMN1; SMN2TDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL701358 | 0.80 | MEN1 (0.49) | SMN1; SMN2TDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL28912642 | 0.80 | TSHR (0.49) | TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1 | |
| SCHEMBL700297 | 0.79 | TSHR (0.60) | TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1 | |
| SCHEMBL5803088 | 0.78 | HPGD (0.46) | TSHRSMN1; SMN2HSD17B10ALDH1A1MEN1 | |
| SCHEMBL5803087 | 0.78 | HPGD (0.46) | TSHRSMN1; SMN2HSD17B10ALDH1A1MEN1 | |
| SCHEMBL9453433 | 0.75 | TSHR (0.55) | TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115784925-B | Continuous preparation method of 2-methyl-6-nitrobenzaldehyde oxime | 江苏七洲绿色科技研究院有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-113717120-B | Preparation method of 3- (2-methyl-6-nitrophenyl) -4, 5-dihydro-isoxazole | 湖南海利常德农药化工有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-115784925-A | Continuous preparation method of 2-methyl-6-nitrobenzaldehyde oxime | 江苏七洲绿色科技研究院有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-114163352-B | Preparation method of 2-methyl-6-nitrobenzaldehyde oxime | 江苏七洲绿色科技研究院有限公司 | 2022-06-10 | — | — | CN | claimed |
| CN-114163352-A | Preparation method of 2-methyl-6-nitrobenzaldehyde oxime | 江苏七洲绿色科技研究院有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-113717120-A | Preparation method of 3- (2-methyl-6-nitrophenyl) -4, 5-dihydroisoxazole | 湖南海利常德农药化工有限公司 | 2021-11-30 | — | — | CN | claimed |
| CN-118788251-B | Method for preparing 3- [ 3-bromo-2-methyl-6- (methylsulfonyl) phenyl ] -4, 5-dihydroisoxazole | 苏州开元民生科技股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-118894789-A | Method for continuously synthesizing alpha-chloro oxime | 苏利(宁夏)新材料科技有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-118788251-A | Method for preparing 3- [ 3-bromo-2-methyl-6- (methylsulfonyl) phenyl ] -4, 5-dihydroisoxazole | 苏州开元民生科技股份有限公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-115784925-B | Continuous preparation method of 2-methyl-6-nitrobenzaldehyde oxime | 江苏七洲绿色科技研究院有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-115784925-B | Continuous preparation method of 2-methyl-6-nitrobenzaldehyde oxime | 江苏七洲绿色科技研究院有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-115784925-B | Continuous preparation method of 2-methyl-6-nitrobenzaldehyde oxime | 江苏七洲绿色科技研究院有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-113717120-B | Preparation method of 3- (2-methyl-6-nitrophenyl) -4, 5-dihydro-isoxazole | 湖南海利常德农药化工有限公司 | 2023-06-27 | — | — | CN | disclosed |
| US-20030018200-A1 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2003-01-23 | — | — | US | disclosed |
| US-6469176-B1 | CROP PROTECTION COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | disclosed |
| EP-1129082-A1 | METHOD AND NOVEL INTERMEDIATE PRODUCTS FOR PRODUCING ISOXAZOLIN-3-YL-ACYLBENZENES | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-05 | — | — | EP | disclosed |
| CN-1300284-A | Preparation of isoxazolin-3-yl-acylbenzenes | BASF AG (DE) | 2001-06-20 | — | — | CN | disclosed |
| EP-1077955-A1 | METHOD FOR PRODUCING ISOXAZOLINE-3-YL-ACYL BENZENE | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000029394-A1 | METHOD AND NOVEL INTERMEDIATE PRODUCTS FOR PRODUCING ISOXAZOLIN-3-YL-ACYLBENZENES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-25 | — | — | WO | disclosed |
| WO-1999058509-A1 | METHOD FOR PRODUCING ISOXAZOLINE-3-YL-ACYL BENZENE | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018200-A1 | Preparation of isoxazolin-3-ylacylbenzenes | CYP2F1, UQCRB, CYP1B1 | TSHR 588/4885SMN1; SMN2 4220/4885HSD17B10 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.