Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.44 |
| ▸ | NPC1 | O15118 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4599310 | 0.77 | RAB9A (0.50) | RAB9ANPC1MAPTPOLBCASP3 | |
| SCHEMBL21060525 | 0.77 | ESRRG (0.52) | RAB9ANPC1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL6622210 | 0.76 | HPGD (0.54) | RAB9ANPC1HPGDNAMPTSMN1; SMN2 | |
| SCHEMBL357988 | 0.75 | TP53 (0.49) | RAB9ANPC1HPGDSMN1; SMN2HTT | |
| SCHEMBL16145989 | 0.74 | TP53 (0.50) | RAB9ANPC1SMN1; SMN2HTTPOLB | |
| SCHEMBL6812253 | 0.73 | SMN1; SMN2 (0.45) | RAB9ANPC1SMN1; SMN2HTTPOLB | |
| SCHEMBL20037576 | 0.73 | EPHX2 (0.51) | RAB9ANPC1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL21060558 | 0.73 | MEN1 (0.61) | RAB9ANPC1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL6812179 | 0.73 | SMN1; SMN2 (0.44) | RAB9ANPC1SMN1; SMN2HTTPOLB | |
| SCHEMBL358780 | 0.72 | ALDH1A1 (0.50) | RAB9ANPC1HPGDSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345930-A2 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050067-A2 | PHARMACEUTICAL HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 2002-06-27 | — | — | WO | disclosed |