Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993558 | 0.89 | MAPT (0.41) | MAPTXBP1TDP1PLA2G1BATG4B | |
| SCHEMBL6993715 | 0.87 | GRIA2 (0.47) | MAPTXBP1TDP1PLA2G1BATG4B | |
| SCHEMBL7001539 | 0.85 | MAPT (0.51) | MAPTXBP1TDP1PLA2G1BATG4B | |
| SCHEMBL7447280 | 0.84 | CHRM1 (0.43) | MAPTXBP1TDP1PLA2G1BATG4B | |
| SCHEMBL7226695 | 0.83 | GRIA2 (0.47) | MAPTXBP1TDP1PLA2G1BATG4B | |
| SCHEMBL7225951 | 0.82 | MAPT (0.52) | MAPTXBP1TDP1PLA2G1BATG4B | |
| SCHEMBL7234076 | 0.80 | CYP1A2 (0.49) | MAPTXBP1TDP1PLA2G1BATG4B | |
| SCHEMBL7607849 | 0.77 | CYP1A2 (0.61) | MAPTXBP1TDP1PLA2G1BATG4B | |
| SCHEMBL6997430 | 0.76 | GRIA2 (0.46) | MAPTXBP1TDP1PLA2G1BATG4B | |
| SCHEMBL6935103 | 0.76 | MAPT (0.44) | MAPTTDP1LMNAHSD17B10EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001956-B1 | 2,3-BENZODIAZEPINE DERIVATIVES | GYOGYSZERKUTATO INTEZET (HU) | 2003-05-07 | — | — | EP | disclosed |
| US-6482819-B1 | 2,3-benzodiazepine derivatives | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2002-11-19 | — | — | US | disclosed |