Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7609618 | 0.90 | APP (0.43) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL6935668 | 0.89 | MAPT (0.44) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL6933786 | 0.89 | PSD (0.44) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL7498251 | 0.85 | KMT2A (0.44) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL6937957 | 0.84 | MAPT (0.44) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL10886471 | 0.83 | APP (0.51) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL7492463 | 0.82 | MAPT (0.69) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL7606361 | 0.80 | APP (0.43) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL6290909 | 0.79 | HTT (0.50) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL9223260 | 0.79 | MAPT (0.47) | MAPTMEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802195-B1 | Substituted 2,3-benzodiazepine derivatives, process and intermediates for their preparation and pharmaceutical compositions comprising them as well as their use | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2003-11-19 | — | — | EP | disclosed |
| US-5807851-A | MUSCLE RELAXANTS; NERVOUS SYSTEM DISORDERS | EGIS GYOGYSZERGYAR RT. (HU) | 1998-09-15 | — | — | US | disclosed |
| EP-0802195-A2 | Substituted 2,3-benzodiazepine derivatives, process and intermediates for their preparation and pharmaceutical compositions comprising them as well as their use | EGIS GYOGYSZERGYAR RT. (HU) | 1997-10-22 | — | — | EP | disclosed |