Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 17/20 | 0.37 |
| ▸ | F3 | P13726 | 17/20 | 0.37 |
| ▸ | F2 | P00734 | 13/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456064 | 0.78 | BRD4 (0.46) | F7F3F2 | |
| SCHEMBL1734473 | 0.60 | KDM4E (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL141474 | 0.57 | GAA (0.58) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9282392 | 0.56 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8128443 | 0.56 | MAPT (0.68) | — | |
| SCHEMBL22261077 | 0.56 | JAK3 (0.54) | PLAU | |
| SCHEMBL2850380 | 0.55 | HPGD (0.60) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL11248471 | 0.55 | GAA (0.46) | ALDH1A1 | |
| SCHEMBL3455667 | 0.54 | GAA (0.57) | SMN1; SMN2PRSS1 | |
| SCHEMBL7504776 | 0.54 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292579-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRAZINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | Pharmacia Corporation (US) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001087854-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRAZINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-11-22 | — | — | WO | disclosed |