Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 6/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 6/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6990621 | 0.99 | AXL (0.41) | AXLCHRM3PDE4APDE4BPDE4C | |
| SCHEMBL6996668 | 0.88 | AXL (0.40) | AXLCHRM3PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL6992368 | 0.87 | AXL (0.39) | AXLCHRM3PDE4APDE4BPDE4C | |
| SCHEMBL6991702 | 0.87 | CHRM3 (0.46) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL6990935 | 0.86 | CHRM3 (0.45) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7817704 | 0.86 | HPGD (0.46) | KDM4EPOLBMAPTNR2F2MAPK1 | |
| SCHEMBL6998551 | 0.85 | GRIN2D (0.43) | AXLKDM4EPOLBMAPTNR2F2 | |
| Hydrochloric Acid SCHEMBL7824694 | 0.85 | LMNA (0.48) | KDM4EPOLBMAPTMAPK1RAB9A | |
| Hydrochloric Acid SCHEMBL6969212 | 0.85 | CHRM3 (0.39) | AXLCHRM3PDE4APDE4BPDE4C | |
| SCHEMBL6997622 | 0.85 | MEN1 (0.45) | CHRM3PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775120-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2003-06-04 | — | — | EP | claimed |