SCHEMBL6996963

SCHEMBL6996963

CNC(c1ccncc1)c1ccc2c(c1)N=C(N)C(C)O2

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6991858 0.99 CYP3A4 (0.33) CYP3A4CYP2C19
Hydrochloric Acid SCHEMBL7704887 0.85 POLB (0.33) CYP3A4
SCHEMBL7001782 0.81
SCHEMBL6996663 0.73 SLC6A4 (0.34)
SCHEMBL6989627 0.72 PARP1 (0.45) CYP3A4CYP2C19
SCHEMBL7001034 0.72 LMNA (0.33) CYP3A4
SCHEMBL7985549 0.68 MAPT (0.43) CYP3A4
SCHEMBL6611984 0.66 PARP1 (0.45)
SCHEMBL15787497 0.64 CYP3A4 (0.54) CYP3A4CYP2C19
SCHEMBL15787302 0.64 CYP3A4 (0.54) CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1015437-B1 BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS SCHERING AG (DE) 2003-12-03 EP claimed