Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 5/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7000249 | 0.91 | KDM4E (0.39) | PTGS2PTGS1ELANEAKR1C3AKR1C2 | |
| SCHEMBL6997585 | 0.87 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL6996469 | 0.86 | PTGS2 (0.50) | PTGS2PTGS1ELANE | |
| SCHEMBL6994338 | 0.86 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL6995060 | 0.85 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL6997443 | 0.84 | AKR1C3 (0.38) | PTGS1AKR1C3AKR1C2 | |
| SCHEMBL6995804 | 0.83 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL7002103 | 0.82 | AKR1C3 (0.38) | PTGS1AKR1C3AKR1C2 | |
| SCHEMBL6997003 | 0.82 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL6999885 | 0.82 | PTGS2 (0.50) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109799-B1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-12-17 | — | — | EP | claimed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | claimed |
| EP-1109799-B1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-12-17 | — | — | EP | disclosed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | disclosed |