Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL951186 | 0.89 | DUT (0.33) | DUT | |
| SCHEMBL4336626 | 0.89 | DUT (0.36) | DUT | |
| SCHEMBL11580466 | 0.81 | DUT (0.42) | DUT | |
| SCHEMBL16782083 | 0.76 | DUT (0.38) | DUT | |
| SCHEMBL25899606 | 0.76 | — | — | |
| SCHEMBL12380487 | 0.76 | TDP1 (0.40) | — | |
| SCHEMBL8063404 | 0.76 | DUT (0.43) | DUT | |
| SCHEMBL16782051 | 0.75 | DUT (0.37) | DUT | |
| SCHEMBL3509611 | 0.74 | DUT (0.35) | DUT | |
| SCHEMBL9007756 | 0.74 | DUT (0.42) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178469-A | Oligonucleotide modified podophyllotoxin derivative and preparation method and application thereof | 汤亚杰 | 2023-05-30 | — | — | CN | disclosed |
| EP-0975636-B1 | 1H-PYRAZOLO[3,4-D]PYRIMIDINE-4,6-DIONES AS T-CELL PROLIFERATION INHIBITORS | ASTRAZENECA AB (SE) | 2003-07-23 | — | — | EP | disclosed |
| US-6403584-B1 | CONJUNCTIVITIS, ALLERGIC RHINITIS, ALZHEIMER'S DISEASE, ASTHMA, ATHEROSCLEROSIS, AUTOLOGOUS BONE MARROW TRANSPLANTATION, ANTIINFLAMMATORY, ETC | MERCK & CO., INC. | 2002-06-11 | — | — | US | disclosed |
| US-6229013-B1 | PRODUCED BY HYDROGENATION AND DEHALOGENATION IN THE PRESENCE OF A CATALYST; ANTIINFLAMMATORY AGENTS, IMMUNOSUPRESSANTS, ANTIPROLIFERATIVE AGENTS, ANTICARCINOGENIC AGENTS, AND TREATMENT OF RHEUMATIC DISEASE | ASTRAZENECA UK LIMITED (GB) | 2001-05-08 | — | — | US | disclosed |
| US-6166206-A | Pyrrolo[3,4-D]Pyrimidinone derivatives and their use as medicaments | ASTRAZENECA UK LIMITED (GB) | 2000-12-26 | — | — | US | disclosed |
| US-6136974-A | Pyrrolo[3,4-D]Pyrimidinone derivatives and their use as medicaments | ASTRAZENECA UK LIMITED (GB) | 2000-10-24 | — | — | US | disclosed |
| US-6046204-A | Pyrrolo[3,4-D] pyrimidinone derivatives and their use as medicaments | ASTRA PHARMACEUTICALS LIMITED (GB) | 2000-04-04 | — | — | US | disclosed |
| US-6028074-A | FOR TREATING ALLOGRAFT REJECTION | ASTRA PHARMACEUTICALS, LTD. (GB) | 2000-02-22 | — | — | US | disclosed |