SCHEMBL951186

SCHEMBL951186

CC(C)(C)[Si](C)(C)OCCSSCCO

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6997516 0.89 DUT (0.37) DUT
SCHEMBL4336626 0.88 DUT (0.36) DUT
SCHEMBL12380487 0.84 TDP1 (0.40)
SCHEMBL31326668 0.79 HTR1A (0.33) DUT
SCHEMBL738264 0.78 DUT (0.34) DUT
SCHEMBL571057 0.74 DUT (0.39) DUT
SCHEMBL14760492 0.73 DUT (0.34) DUT
Ammonia Solution, Strong SCHEMBL9187414 0.72 DUT (0.38) DUT
SCHEMBL334934 0.72 DUT (0.38) DUT
SCHEMBL11580466 0.72 DUT (0.42) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743440-A1 IONIZABLE LIPIDS eTheRNA immunotherapies NV (BE) 2026-05-20 EP disclosed
WO-2025012376-A1 IONIZABLE LIPIDS ETHERNA IMMUNOTHERAPIES NV (BE) 2025-01-16 WO disclosed
US-9744183-B2 Nucleic acid prodrugs and methods of use thereof WAVE LIFE SCIENCES LTD. (SG) 2017-08-29 US disclosed
US-20120316224-A1 NOVEL NUCLEIC ACID PRODRUGS AND METHODS OF USE THEREOF ONTORII, INC (US) 2012-12-13 US disclosed
EP-2451461-A1 NOVEL NUCLEIC ACID PRODRUGS AND METHODS OF USE THEREOF Ontorii, Inc (US) 2012-05-16 EP disclosed
WO-2011005761-A1 NOVEL NUCLEIC ACID PRODRUGS AND METHODS USE THEREOF ONTORII, INC (US) 2011-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120316224-A1 NOVEL NUCLEIC ACID PRODRUGS AND METHODS OF USE THEREOF PNP, RNGTT, TYMP DUT 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.