Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16394026 | 1.00 | SLC6A4 (0.41) | SLC6A4MAPTNR1H2NR1H3DRD2 | |
| SCHEMBL5744290 | 0.90 | SLC6A4 (0.46) | SLC6A4MAPTNR1H2NR1H3DRD2 | |
| SCHEMBL19034819 | 0.85 | MAPT (0.48) | MAPTNR1H2NR1H3DRD2DRD3 | |
| SCHEMBL7005925 | 0.85 | MAPT (0.39) | SLC6A4MAPTNR1H2NR1H3DRD2 | |
| SCHEMBL16023501 | 0.85 | PDK1 (0.36) | SLC6A4MAPTNR1H2NR1H3DRD2 | |
| SCHEMBL17427527 | 0.85 | PDK1 (0.36) | SLC6A4MAPTNR1H2NR1H3DRD2 | |
| SCHEMBL3833437 | 0.77 | PTPN1 (0.48) | DRD2SIGMAR1 | |
| SCHEMBL5745904 | 0.77 | NR1H2 (0.43) | MAPTNR1H2NR1H3SIGMAR1 | |
| SCHEMBL10522832 | 0.77 | PTPN1 (0.48) | DRD2SIGMAR1 | |
| SCHEMBL13379049 | 0.77 | PTPN1 (0.48) | DRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792273-B1 | BICYCLIC OXAZINE AND THIAZINE OXAZOLIDINONE ANTIBACTERIALS | UPJOHN CO (US) | 2003-03-05 | — | — | EP | disclosed |
| US-5952324-A | BACTERICIDES AGAINST A NUMBER OF HUMAN AND VETERINARY PATHOGENS, INCLUDING GRAMPOSITIVE AEROBIC BACTERIA SUCH AS STAPHYLOCOCCI, STREPTOCOCCI, ENTEROCOCCI AND ANAEROBIC ORGANISMS SUCH AS BACTEROIDES, CLOSTRIDIA AND MYCOBACTERIUM | PHARMACIA & UPJOHN COMPANY (US) | 1999-09-14 | — | — | US | disclosed |