Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 20/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 20/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7000349 | 0.90 | MTNR1A (0.51) | MTNR1AMTNR1BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL5368769 | 0.86 | MTNR1A (0.50) | MTNR1AMTNR1BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL5361550 | 0.84 | MTNR1A (0.67) | MTNR1AMTNR1BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7004573 | 0.83 | MTNR1A (0.40) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL5367094 | 0.82 | MTNR1A (0.55) | MTNR1AMTNR1BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL5369933 | 0.82 | MTNR1A (0.54) | MTNR1AMTNR1BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL5371034 | 0.81 | MTNR1A (0.69) | MTNR1AMTNR1BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL6995494 | 0.81 | MTNR1A (0.39) | MTNR1AMTNR1BMAPT | |
| SCHEMBL7000833 | 0.80 | MTNR1A (0.38) | MTNR1AMTNR1B | |
| SCHEMBL18661751 | 0.79 | MTNR1A (0.51) | MTNR1AMTNR1BKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092717-B1 | Polycyclic azaindole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-01-08 | — | — | EP | claimed |