Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 16/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5367177 | 0.86 | SMN1; SMN2 (0.46) | MTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL6997653 | 0.83 | MTNR1A (0.49) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL7000349 | 0.80 | MTNR1A (0.51) | MTNR1AMTNR1BKDM4EALDH1A1LMNA | |
| SCHEMBL6995494 | 0.77 | MTNR1A (0.39) | MTNR1AMTNR1B | |
| SCHEMBL7000833 | 0.76 | MTNR1A (0.38) | MTNR1AMTNR1B | |
| SCHEMBL5368761 | 0.75 | TACR1 (0.36) | MTNR1AMTNR1BKDM4EALDH1A1LMNA | |
| SCHEMBL5368769 | 0.69 | MTNR1A (0.50) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL7000227 | 0.69 | MTNR1A (0.49) | MTNR1AMTNR1BKDM4EALDH1A1LMNA | |
| SCHEMBL5364390 | 0.68 | MTNR1A (0.51) | MTNR1AMTNR1BKDM4EALDH1A1LMNA | |
| SCHEMBL5367185 | 0.67 | MTNR1A (0.53) | MTNR1AMTNR1BKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092717-B1 | Polycyclic azaindole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-01-08 | — | — | EP | claimed |