Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30522562 | 1.00 | IMPDH2 (0.49) | IMPDH2ALDH1A1PDE3BPDE3AAURKB | |
| SCHEMBL8146040 | 0.85 | ALDH1A1 (0.56) | ALDH1A1PDE10AMEN1KMT2ALMNA | |
| SCHEMBL99566 | 0.83 | ALDH1A1 (0.54) | ALDH1A1PDE10AMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL7543824 | 0.81 | ALDH1A1 (0.52) | ALDH1A1PDE10AMEN1KMT2ALMNA | |
| SCHEMBL8953996 | 0.81 | ALDH1A1 (0.52) | ALDH1A1PDE10AMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL10585120 | 0.81 | ALDH1A1 (0.52) | ALDH1A1PDE10AMEN1KMT2ALMNA | |
| SCHEMBL16405694 | 0.81 | IMPDH2 (0.53) | IMPDH2ALDH1A1PDE3BPDE3AAURKB | |
| Methane SCHEMBL28805939 | 0.81 | ALDH1A1 (0.52) | ALDH1A1PDE10AMEN1KMT2ALMNA | |
| SCHEMBL311241 | 0.81 | ALDH1A1 (0.56) | ALDH1A1PDE10AMEN1KMT2ANPC1 | |
| SCHEMBL30026852 | 0.81 | ALDH1A1 (0.56) | ALDH1A1PDE10AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227427-A1 | IL-17A MODULATORS | SANOFI (FR) | 2023-07-20 | — | — | US | disclosed |
| EP-4157827-A1 | IL-17A MODULATORS | SANOFI (FR) | 2023-04-05 | — | — | EP | disclosed |
| WO-2021239743-A1 | IL-17A MODULATORS | SANOFI (FR) | 2021-12-02 | — | — | WO | disclosed |
| EP-1003738-B1 | BICYCLIC COMPOUNDS AS LIGANDS FOR 5-HT1 RECEPTORS | SMITHKLINE BEECHAM PLC (GB) | 2003-11-19 | — | — | EP | disclosed |
| US-6391891-B1 | ANTISEROTONINE AGENT; ANXIOLYTIC AGENTS, ANTIDEPRESSANTS | SMITHKLINE BEECHAM PLC (GB) | 2002-05-21 | — | — | US | disclosed |
| EP-1003738-A1 | BICYCLIC COMPOUNDS AS LIGANDS FOR 5-HT1 RECEPTORS | SMITHKLINE BEECHAM PLC (GB) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007700-A1 | BICYCLIC COMPOUNDS AS LIGANDS FOR 5-HT1 RECEPTORS | SMITHKLINE BEECHAM PLC (GB) | 1999-02-18 | — | — | WO | disclosed |
| US-4506075-A | PYRIDINE, BENZOYL CHLORIDE, 3-METHYL-N,N-DIALKYLBENZENEAMINE, COPPER | STERLING DRUG INC. (US) | 1985-03-19 | — | — | US | disclosed |
| US-4506075-A | PYRIDINE, BENZOYL CHLORIDE, 3-METHYL-N,N-DIALKYLBENZENEAMINE, COPPER | STERLING DRUG INC. (US) | 1985-03-19 | — | — | US | disclosed |
| US-4506075-A | PYRIDINE, BENZOYL CHLORIDE, 3-METHYL-N,N-DIALKYLBENZENEAMINE, COPPER | STERLING DRUG INC. (US) | 1985-03-19 | — | — | US | disclosed |
| US-4415578-A | INOTROPIC AGENTS | STERLING DRUG INC. (US) | 1983-11-15 | — | — | US | disclosed |
| US-4415578-A | INOTROPIC AGENTS | STERLING DRUG INC. (US) | 1983-11-15 | — | — | US | disclosed |
| US-4415578-A | INOTROPIC AGENTS | STERLING DRUG INC. (US) | 1983-11-15 | — | — | US | disclosed |
| EP-0089394-A1 | 1-H-Indole-2,3-dione derivatives and preparation thereof | STERLING DRUG INC. (US) | 1983-09-28 | — | — | EP | disclosed |
| US-4322533-A | CARDIOTONIC, BRONCHODILATOR, AND ANTICHLOLINERGIC AGENTS; ANTIMISTAMINES; ANTIALLERGENS | STERLING DRUG INC. | 1982-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227427-A1 | IL-17A MODULATORS | IL17A, IL2, IL15 | IMPDH2 3096/4885ALDH1A1 485/4885PDE3B 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.