SCHEMBL6997864

SCHEMBL6997864

Cc1cc(O)c(C(=O)C=CC(C)C)c(=O)o1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 11/20 0.62
KMT2A Q03164 11/20 0.62
RAB9A P51151 5/20 0.62
NPC1 O15118 3/20 0.62
POLB P06746 3/20 0.60
MAPT P10636 6/20 0.59
PKM P14618 3/20 0.59
KDM4E B2RXH2 2/20 0.59
RECQL P46063 2/20 0.59
GAA P10253 2/20 0.59
HTT P42858 1/20 0.59
USP2 O75604 3/20 0.58
PPARG P37231 2/20 0.58
L3MBTL1 Q9Y468 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.55
NPSR1 Q6W5P4 2/20 0.54
PLIN1 O60240 1/20 0.54
ALOX12 P18054 1/20 0.54
PLIN5 Q00G26 1/20 0.54
ABHD5 Q8WTS1 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6997861 1.00 MEN1 (0.62) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL21676884 0.86 KMT2A (0.57) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL10519529 0.81 MEN1 (0.63) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL27921560 0.79 MEN1 (0.60) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL7607429 0.76 FFAR1 (0.53) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL5150395 0.75 MEN1 (0.81) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL10618566 0.75 MEN1 (0.76) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL5150390 0.75 MEN1 (0.81) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL10618560 0.75 MEN1 (0.76) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL29946098 0.74 MEN1 (1.00) MEN1KMT2ARAB9ANPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1193263-B1 Process for producing pyrone compounds SUMITOMO CHEMICAL CO (JP) 2003-09-03 EP claimed
US-6420569-B1 Process for producing pyrone compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-07-16 US claimed
US-20020042525-A1 Process for producing pyrone compounds SUMITOMO CHEMICAL COMPANY, LIMITED 2002-04-11 US claimed
EP-1193263-A1 Process for producing pyrone compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-03 EP claimed
CN-103360308-A 1,4-dyhydroxy-6-methyl-2-pyridine ketone compound, and preparation method and use thereof SUN WEIXIN 2013-10-23 CN disclosed
CN-1176917-C Prep. of pyrone compound ס�ѻ�ѧ��ҵ��ʽ���� 2004-11-24 CN disclosed
EP-1193263-B1 Process for producing pyrone compounds SUMITOMO CHEMICAL CO (JP) 2003-09-03 EP disclosed
JP-2002201189-A METHOD FOR PRODUCING PYRONE COMPOUND SUMITOMO CHEM CO LTD 2002-07-16 JP disclosed
JP-2002201190-A METHOD FOR PRODUCING PYRONE COMPOUND SUMITOMO CHEM CO LTD 2002-07-16 JP disclosed
US-6420569-B1 Process for producing pyrone compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-07-16 US disclosed
US-6420569-B1 Process for producing pyrone compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-07-16 US disclosed
JP-2002161090-A METHOD FOR PRODUCING PYRONE COMPOUND SUMITOMO CHEM CO LTD 2002-06-04 JP disclosed
CN-1344714-A Prep. of pyrone compound SUMITOMO CHEMICAL CO (JP) 2002-04-17 CN disclosed
JP-2002114772-A METHOD OF PRODUCING PYRONE SUMITOMO CHEM CO LTD 2002-04-16 JP disclosed
US-20020042525-A1 Process for producing pyrone compounds SUMITOMO CHEMICAL COMPANY, LIMITED 2002-04-11 US disclosed
US-20020042525-A1 Process for producing pyrone compounds SUMITOMO CHEMICAL COMPANY, LIMITED 2002-04-11 US disclosed
EP-1193263-A1 Process for producing pyrone compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-03 EP disclosed
EP-1193263-A1 Process for producing pyrone compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-03 EP disclosed
WO-2002014300-A1 PROCESSES FOR THE PRODUCTION OF PYRONE COMPOUNDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-21 WO disclosed
WO-2002004436-A1 PROCESSES FOR THE PREPARATION OF PYRONE COMPOUNDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020042525-A1 Process for producing pyrone compounds TET2, PF4, TET3 MEN1 508/4885KMT2A 1098/4885RAB9A 2199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.