Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987357 | 0.91 | MEN1 (0.42) | TAS1R3TAS1R1MEN1KMT2AANO1 | |
| SCHEMBL4425768 | 0.89 | TAS1R3 (0.46) | TAS1R3TAS1R1MEN1KMT2AANO1 | |
| SCHEMBL8862522 | 0.88 | TAS1R3 (0.49) | TAS1R3TAS1R1MEN1KMT2AALDH1A1 | |
| SCHEMBL8556633 | 0.86 | TAS1R3 (0.47) | TAS1R3TAS1R1ANO1ALDH1A1 | |
| SCHEMBL6992821 | 0.84 | TAS1R3 (0.45) | TAS1R3TAS1R1KMT2AANO1HPGD | |
| SCHEMBL7960894 | 0.81 | MEN1 (0.44) | MEN1KMT2AANO1ALDH1A1HPGD | |
| SCHEMBL7949760 | 0.81 | TAS1R3 (0.44) | TAS1R3TAS1R1KMT2AALDH1A1HPGD | |
| SCHEMBL8862570 | 0.80 | TAS1R3 (0.41) | TAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL4428398 | 0.80 | TAS1R3 (0.46) | TAS1R3TAS1R1MEN1KMT2AANO1 | |
| SCHEMBL4424507 | 0.80 | MEN1 (0.41) | TAS1R3TAS1R1MEN1KMT2AANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754175-B1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| WO-1995026954-A1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-12 | — | — | WO | disclosed |