Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | MMP16 | P51512 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958008 | 0.89 | SHMT1 (0.50) | MEN1KMT2AANO1ALDH1A1HPGD | |
| SCHEMBL6474981 | 0.86 | MEN1 (0.46) | MEN1KMT2AANO1ALDH1A1SHMT1 | |
| SCHEMBL7964621 | 0.84 | MEN1 (0.43) | MEN1KMT2AANO1ALDH1A1HPGD | |
| SCHEMBL8651766 | 0.83 | P2RX7 (0.47) | ANO1ALDH1A1SHMT1HTT | |
| SCHEMBL6997846 | 0.83 | MEN1 (0.41) | MEN1KMT2AANO1ALDH1A1HPGD | |
| SCHEMBL6998326 | 0.81 | TAS1R3 (0.47) | MEN1KMT2AANO1ALDH1A1HPGD | |
| SCHEMBL7960614 | 0.81 | CYP3A4 (0.40) | MEN1KMT2AHPGDSHMT1HTT | |
| SCHEMBL8569927 | 0.81 | MEN1 (0.49) | MEN1KMT2AALDH1A1HPGDAPOBEC3A | |
| SCHEMBL7960768 | 0.78 | MEN1 (0.46) | MEN1KMT2AANO1ALDH1A1HPGD | |
| SCHEMBL3927575 | 0.78 | MEN1 (0.44) | MEN1KMT2AALDH1A1HPGDAPOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |