Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310321 | 0.89 | F13A1 (0.43) | FBP1ERN1MAPTKMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL7313325 | 0.88 | F13A1 (0.42) | FBP1ERN1MAPTKMT2ATDP1 | |
| SCHEMBL1573514 | 0.84 | ALDH1A1 (0.56) | FBP1ALDH1A1TSHRKDM4EKMT2A | |
| SCHEMBL6002942 | 0.84 | ALDH1A1 (0.56) | FBP1ALDH1A1TSHRKDM4EKMT2A | |
| SCHEMBL28961939 | 0.83 | ERN1 (0.47) | ERN1MAPTGPR35ALDH1A1TSHR | |
| SCHEMBL30166416 | 0.80 | FBP1 (0.48) | FBP1MAPTFFAR1GPR35GRIA2 | |
| SCHEMBL28138111 | 0.80 | FBP1 (0.48) | FBP1FFAR1GPR35GRIA2ALDH1A1 | |
| SCHEMBL10939157 | 0.80 | GRIA2 (0.50) | FBP1FFAR1GPR35GRIA2ALDH1A1 | |
| SCHEMBL11338808 | 0.80 | TDP1 (0.55) | FBP1FFAR1GPR35GRIA2ALDH1A1 | |
| SCHEMBL10628178 | 0.80 | ALDH1A1 (0.50) | ERN1MAPTALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1241169-B1 | Isoindoloindolone derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-08-27 | — | — | EP | disclosed |
| US-6465660-B1 | PARTICULARLY 2-HYDROXY-8,9-DIMETHOXYISOINDOLO(2,1-A)INDOL-6-ONE AND 2-HYDROXY-8,9-DIMETHOXYISOINDOLO(2,1-A)INDOL-6-ONE; TREATING A DISORDER OF THE MELATONINERGIC SYSTEM | LES LABORATOIRES SERVIER (FR) | 2002-10-15 | — | — | US | disclosed |
| EP-1241169-A1 | Isoindoloindolone derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2002-09-18 | — | — | EP | disclosed |