Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149379 | 0.85 | FFAR1 (0.51) | KMOFFAR1IDO1SLC6A3SLC6A4 | |
| SCHEMBL8152908 | 0.85 | FFAR1 (0.51) | KMOFFAR1IDO1SLC6A3SLC6A4 | |
| SCHEMBL7003669 | 0.85 | FFAR1 (0.51) | KMOFFAR1IDO1SLC6A3SLC6A4 | |
| SCHEMBL7002253 | 0.85 | FFAR1 (0.51) | KMOFFAR1IDO1SLC6A3SLC6A4 | |
| SCHEMBL29879365 | 0.85 | FFAR1 (0.49) | KMOFFAR1IDO1 | |
| SCHEMBL24737999 | 0.85 | FFAR1 (0.49) | KMOFFAR1IDO1 | |
| SCHEMBL8149382 | 0.85 | FFAR1 (0.51) | KMOFFAR1IDO1SLC6A3SLC6A4 | |
| SCHEMBL8152906 | 0.85 | FFAR1 (0.51) | KMOFFAR1IDO1SLC6A3SLC6A4 | |
| SCHEMBL7002249 | 0.85 | FFAR1 (0.51) | KMOFFAR1IDO1SLC6A3SLC6A4 | |
| SCHEMBL7003675 | 0.85 | FFAR1 (0.51) | KMOFFAR1IDO1SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996621-B1 | TRIAZOLO[4,5-d]PYRIMIDINE DERIVATIVES AS ANTI-THROMBOTIC AGENTS | ASTRAZENECA AB (SE) | 2003-10-01 | — | — | EP | disclosed |
| US-6251910-B1 | 1,2,3-triazolo[4,5-d]pyrimidines as P2T receptor antagonists | ASTRAZENECA UK LIMITED (GB) | 2001-06-26 | — | — | US | disclosed |