Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 16/20 | 0.74 |
| ▸ | NR3C2 | P08235 | 10/20 | 0.74 |
| ▸ | AR | P10275 | 10/20 | 0.74 |
| ▸ | PGR | P06401 | 14/20 | 0.71 |
| ▸ | ESR1 | P03372 | 5/20 | 0.71 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6294998 | 0.91 | NR3C1 (0.75) | NR3C1NR3C2ARPGRESR1 | |
| Acetic Acid SCHEMBL6291027 | 0.88 | NR3C1 (0.74) | NR3C1NR3C2ARPGRESR1 | |
| SCHEMBL6294953 | 0.88 | NR3C1 (0.80) | NR3C1NR3C2ARPGRESR1 | |
| SCHEMBL6290327 | 0.87 | PGR (0.78) | NR3C1NR3C2ARPGRESR1 | |
| SCHEMBL6291028 | 0.86 | NR3C1 (0.79) | NR3C1NR3C2ARPGRESR1 | |
| SCHEMBL6291168 | 0.85 | NR3C1 (0.72) | NR3C1NR3C2ARPGRESR1 | |
| SCHEMBL4171493 | 0.85 | NR3C1 (1.00) | NR3C1NR3C2ARPGRESR1 | |
| SCHEMBL6291115 | 0.85 | PGR (0.78) | NR3C1NR3C2ARPGRESR1 | |
| SCHEMBL6291126 | 0.85 | NR3C1 (0.75) | NR3C1NR3C2ARPGRESR1 | |
| SCHEMBL6291062 | 0.84 | NR3C1 (0.71) | NR3C1NR3C2ARPGRESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053239-B1 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | ABBOTT LAB (US) | 2003-01-08 | — | — | EP | claimed |