Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6999489 | 1.00 | TDP1 (0.54) | TDP1L3MBTL1HRH3HRH4IDO1 | |
| SCHEMBL7003895 | 0.95 | L3MBTL1 (0.60) | TDP1L3MBTL1HRH3HRH4IDO1 | |
| SCHEMBL6996517 | 0.95 | L3MBTL1 (0.60) | TDP1L3MBTL1HRH3HRH4IDO1 | |
| SCHEMBL7003028 | 0.93 | L3MBTL1 (0.63) | TDP1L3MBTL1HRH3HRH4IDO1 | |
| SCHEMBL7004214 | 0.93 | L3MBTL1 (0.63) | TDP1L3MBTL1HRH3HRH4IDO1 | |
| SCHEMBL7006623 | 0.93 | L3MBTL1 (0.63) | TDP1L3MBTL1HRH3HRH4IDO1 | |
| SCHEMBL7001416 | 0.93 | L3MBTL1 (0.63) | TDP1L3MBTL1HRH3HRH4IDO1 | |
| SCHEMBL7001053 | 0.89 | TSHR (0.52) | TDP1L3MBTL1HRH3HRH4IDO1 | |
| SCHEMBL7006090 | 0.89 | TSHR (0.52) | TDP1L3MBTL1HRH3HRH4IDO1 | |
| SCHEMBL4069939 | 0.89 | TDP1 (0.64) | TDP1L3MBTL1HRH3HRH4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069126-B1 | TRIAZOLOPURINE DERIVATIVES, MEDICINAL COMPOSITION CONTAINING THE DERIVATIVES, ADENOSINE A3 RECEPTOR COMPATIBILIZING AGENT, AND ASTHMATIC REMEDY | OTSUKA PHARMA CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-6288070-B1 | Triazolopurine derivatives, medicinal composition containing the derivatives, adenosine A3 receptor compatibilizing agent, and asthmatic remedy | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-09-11 | — | — | US | disclosed |
| EP-1069126-A1 | TRIAZOLOPURINE DERIVATIVES, MEDICINAL COMPOSITION CONTAINING THE DERIVATIVES, ADENOSINE A3 RECEPTOR COMPATIBILIZING AGENT, AND ASTHMATIC REMEDY | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-01-17 | — | — | EP | disclosed |