Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006623 | 1.00 | L3MBTL1 (0.63) | L3MBTL1TDP1TSHRSPHK1NAAA | |
| SCHEMBL7001416 | 1.00 | L3MBTL1 (0.63) | L3MBTL1TDP1TSHRSPHK1NAAA | |
| SCHEMBL7004214 | 1.00 | L3MBTL1 (0.63) | L3MBTL1TDP1TSHRSPHK1NAAA | |
| SCHEMBL6996517 | 0.98 | L3MBTL1 (0.60) | L3MBTL1TDP1TSHRSPHK1NAAA | |
| SCHEMBL7003895 | 0.98 | L3MBTL1 (0.60) | L3MBTL1TDP1TSHRSPHK1NAAA | |
| SCHEMBL6999489 | 0.93 | TDP1 (0.54) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL6998625 | 0.93 | TDP1 (0.54) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL3446778 | 0.89 | TDP1 (0.75) | L3MBTL1TDP1TSHRSPHK1HRH4 | |
| SCHEMBL20534698 | 0.89 | TDP1 (0.75) | L3MBTL1TDP1TSHRSPHK1HRH4 | |
| SCHEMBL7001053 | 0.86 | TSHR (0.52) | L3MBTL1TDP1TSHRNAAAHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1122033-C | Triazolopurine derivatives, pharmaceutical compositions containing the same | OTSUKE PHARMACEUTICAL FACTORY (JP) | 2003-09-24 | — | — | CN | disclosed |
| EP-1069126-B1 | TRIAZOLOPURINE DERIVATIVES, MEDICINAL COMPOSITION CONTAINING THE DERIVATIVES, ADENOSINE A3 RECEPTOR COMPATIBILIZING AGENT, AND ASTHMATIC REMEDY | OTSUKA PHARMA CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-6288070-B1 | Triazolopurine derivatives, medicinal composition containing the derivatives, adenosine A3 receptor compatibilizing agent, and asthmatic remedy | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-09-11 | — | — | US | disclosed |
| CN-1301266-A | Triazolopurine derivatives, pharmaceutical composition containing the same, adenosine A3 receptor affinity agent, and asthma therapeutic agent | OTSUKA PHARMACEUITCAL FACTORY (JP) | 2001-06-27 | — | — | CN | disclosed |
| EP-1069126-A1 | TRIAZOLOPURINE DERIVATIVES, MEDICINAL COMPOSITION CONTAINING THE DERIVATIVES, ADENOSINE A3 RECEPTOR COMPATIBILIZING AGENT, AND ASTHMATIC REMEDY | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-01-17 | — | — | EP | disclosed |