Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CNR1 | P21554 | 3/20 | 0.64 |
| ▸ | CNR2 | P34972 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.63 |
| ▸ | RELA | Q04206 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193406 | 0.84 | L3MBTL1 (0.63) | L3MBTL1TP53CNR1CNR2SMN1; SMN2 | |
| SCHEMBL210149 | 0.83 | SMN1; SMN2 (0.67) | L3MBTL1TP53CNR1CNR2SMN1; SMN2 | |
| SCHEMBL19380255 | 0.83 | L3MBTL1 (0.66) | L3MBTL1TP53CNR1CNR2SMN1; SMN2 | |
| SCHEMBL5330099 | 0.83 | L3MBTL1 (1.00) | L3MBTL1TP53CNR1CNR2SMN1; SMN2 | |
| SCHEMBL30147568 | 0.80 | ALDH1A1 (0.69) | L3MBTL1TP53CNR1CNR2SMN1; SMN2 | |
| SCHEMBL13407890 | 0.80 | ALDH1A1 (0.69) | L3MBTL1TP53CNR1CNR2SMN1; SMN2 | |
| SCHEMBL1769747 | 0.79 | L3MBTL1 (0.64) | L3MBTL1TP53CNR1CNR2SMN1; SMN2 | |
| SCHEMBL1769743 | 0.79 | L3MBTL1 (0.64) | L3MBTL1TP53CNR1CNR2SMN1; SMN2 | |
| SCHEMBL30248312 | 0.79 | CNR1 (0.75) | L3MBTL1TP53CNR1CNR2SMN1; SMN2 | |
| SCHEMBL14345990 | 0.79 | L3MBTL1 (0.80) | L3MBTL1TP53CNR1CNR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002047762-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2002-06-20 | — | — | WO | disclosed |