Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 11/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6999217 | 0.91 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL7003249 | 0.88 | CHRNA7 (0.38) | CHRNA7CYP2D6PTGS2PTGS1 | |
| SCHEMBL6999485 | 0.88 | CHRNA7 (0.44) | CHRNA7CYP2D6PTGS2PTGS1MAOA | |
| SCHEMBL6999843 | 0.83 | CA1 (0.42) | PTGS2 | |
| SCHEMBL7001035 | 0.83 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL6999365 | 0.82 | PTGS2 (0.41) | CHRNA7CYP2D6PTGS2PTGS1MAOA | |
| SCHEMBL6993143 | 0.82 | PTGS2 (0.52) | CHRNA7CYP2D6PTGS2PTGS1MAOA | |
| SCHEMBL7001917 | 0.81 | CA2 (0.47) | CHRNA7PTGS2PTGS1 | |
| SCHEMBL6996939 | 0.80 | PTGS2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL6994360 | 0.79 | CHRNA7 (0.44) | CHRNA7CYP2D6PTGS2PTGS1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109799-B1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-12-17 | — | — | EP | claimed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | claimed |
| EP-1109799-B1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-12-17 | — | — | EP | disclosed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | disclosed |