Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 12/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10821714 | 0.91 | XDH (0.58) | XDHGSK3BALDH1A1 | |
| SCHEMBL6996532 | 0.90 | XDH (0.64) | XDHGSK3BALDH1A1 | |
| SCHEMBL6999626 | 0.89 | XDH (0.62) | XDHGSK3BALDH1A1 | |
| SCHEMBL6996417 | 0.89 | XDH (0.62) | XDHGSK3BALDH1A1 | |
| SCHEMBL7001027 | 0.89 | XDH (0.62) | XDHGSK3BALDH1A1 | |
| SCHEMBL7001612 | 0.88 | XDH (0.43) | XDHADORA2AADORA1ALDH1A1PGR | |
| SCHEMBL6627107 | 0.81 | MAPK8 (0.38) | XDHALDH1A1 | |
| SCHEMBL6334335 | 0.79 | GABRR1 (0.36) | XDHGSK3BALDH1A1 | |
| SCHEMBL9668908 | 0.76 | XDH (0.50) | XDHGSK3BALDH1A1TP53 | |
| SCHEMBL10821681 | 0.75 | NAMPT (0.51) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069126-B1 | TRIAZOLOPURINE DERIVATIVES, MEDICINAL COMPOSITION CONTAINING THE DERIVATIVES, ADENOSINE A3 RECEPTOR COMPATIBILIZING AGENT, AND ASTHMATIC REMEDY | OTSUKA PHARMA CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-6288070-B1 | Triazolopurine derivatives, medicinal composition containing the derivatives, adenosine A3 receptor compatibilizing agent, and asthmatic remedy | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-09-11 | — | — | US | disclosed |
| EP-1069126-A1 | TRIAZOLOPURINE DERIVATIVES, MEDICINAL COMPOSITION CONTAINING THE DERIVATIVES, ADENOSINE A3 RECEPTOR COMPATIBILIZING AGENT, AND ASTHMATIC REMEDY | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-01-17 | — | — | EP | disclosed |