Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.49 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.47 |
| ▸ | ITGAL | P20701 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992214 | 0.84 | PDE7A (0.59) | PDE7AITGB2ICAM1ITGALKMT2A | |
| SCHEMBL4029446 | 0.81 | PDE7A (0.58) | PDE7AITGB2ICAM1ITGALKMT2A | |
| SCHEMBL3839683 | 0.76 | CYP3A4 (0.46) | KMT2AALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL7187676 | 0.73 | ITGB2 (0.80) | PDE7AITGB2ICAM1ITGALKMT2A | |
| SCHEMBL7829578 | 0.71 | PDE7A (0.49) | PDE7AITGB2ICAM1ITGALKMT2A | |
| SCHEMBL8305856 | 0.71 | ALDH1A1 (0.52) | PDE7AITGB2ICAM1ITGALKMT2A | |
| SCHEMBL3020630 | 0.69 | PDE7A (0.59) | PDE7AITGB2ICAM1ITGALKMT2A | |
| SCHEMBL6852277 | 0.68 | PDE7A (0.79) | PDE7AITGB2ICAM1ITGALKMT2A | |
| SCHEMBL10649800 | 0.68 | KMT2A (0.49) | KMT2AALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL720839 | 0.68 | PDE7A (0.73) | PDE7AITGB2ICAM1ITGALKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117659-B1 | SUBSTITUTED 3-CYANOQUINOLINES AS PROTEIN TYROSINE KINASES INHIBITORS | WYETH CORP (US) | 2003-12-03 | — | — | EP | disclosed |
| US-6288082-B1 | COMPOUNDS SUCH AS 6,7-DIETHOXY-4-(INDAN-5-YLAMINO) -QUINOLINE-3-CARBONITRILE USED AS ANTINEOPLASTIC AGENTS AND IN THE TREATMENT OF POLYCYCSTIC KIDNEY DISEASE | AMERICAN CYANAMID COMPANY | 2001-09-11 | — | — | US | disclosed |