Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL699942 | 0.92 | HTR7 (0.36) | HTR7TMEM97SIGMAR1TDP1 | |
| SCHEMBL700080 | 0.91 | BDKRB1 (0.41) | ALDH1A1HTR7TMEM97SIGMAR1DRD2 | |
| SCHEMBL703139 | 0.90 | BDKRB1 (0.39) | ALDH1A1MAPTLMNANAMPTCASP3 | |
| SCHEMBL10246334 | 0.90 | BDKRB1 (0.39) | ALDH1A1MAPTLMNANAMPTCASP3 | |
| Hydrochloric Acid SCHEMBL704835 | 0.89 | BDKRB1 (0.38) | ALDH1A1MAPTLMNANAMPTCASP3 | |
| SCHEMBL3441912 | 0.89 | DRD2 (0.37) | ALDH1A1ADAMTS4ADAMTS5MAPTHTR7 | |
| SCHEMBL10246317 | 0.86 | BDKRB1 (0.39) | ALDH1A1MAPTNAMPTCASP3CASP7 | |
| SCHEMBL703859 | 0.86 | BDKRB1 (0.39) | ALDH1A1MAPTNAMPTCASP3CASP7 | |
| Hydrochloric Acid SCHEMBL707957 | 0.85 | BDKRB1 (0.39) | ALDH1A1MAPTNAMPTCASP3CASP7 | |
| Hydrochloric Acid SCHEMBL700086 | 0.85 | BDKRB1 (0.39) | ALDH1A1MAPTNAMPTCASP3CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124624-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-02-28 | — | — | US | claimed |
| US-20090264407-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-22 | — | — | US | claimed |
| US-8124624-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-20090264407-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264407-A1 | Substituted Sulfonamide Compounds | CNR1, SUCNR1, OPRL1 | ALDH1A1 958/4885ADAMTS4 4276/4885ADAMTS5 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.