Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 10/20 | 0.38 |
| ▸ | WEE1 | P30291 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22117141 | 0.88 | EGLN3 (0.42) | EGLN3TBXAS1WEE1ALDH1A1TDP1 | |
| SCHEMBL26206833 | 0.86 | TBXAS1 (0.49) | EGLN3TBXAS1WEE1ALDH1A1TDP1 | |
| SCHEMBL20623229 | 0.86 | TBXAS1 (0.49) | EGLN3TBXAS1WEE1ALDH1A1TDP1 | |
| SCHEMBL20622958 | 0.86 | TBXAS1 (0.49) | EGLN3TBXAS1WEE1ALDH1A1TDP1 | |
| SCHEMBL11463256 | 0.84 | EGLN3 (0.45) | EGLN3TBXAS1WEE1ALDH1A1TDP1 | |
| SCHEMBL28774336 | 0.81 | TBXAS1 (0.42) | EGLN3TBXAS1WEE1ALDH1A1TDP1 | |
| SCHEMBL4182495 | 0.81 | EGLN3 (0.38) | EGLN3TBXAS1WEE1ALDH1A1TDP1 | |
| SCHEMBL8032072 | 0.81 | TBXAS1 (0.57) | EGLN3TBXAS1ALDH1A1TDP1 | |
| SCHEMBL4780723 | 0.80 | TBXAS1 (0.40) | EGLN3TBXAS1WEE1ALDH1A1TDP1 | |
| SCHEMBL5966061 | 0.80 | TBXAS1 (0.44) | TBXAS1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155001-A4 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | LION BIOSCIENCE AG (DE) | 2003-05-28 | — | — | EP | claimed |
| US-6417195-B1 | LIBRARIES AND COMBINATORIAL CHEMISTRY | LION BIOSCIENCE AG (DE) | 2002-07-09 | — | — | US | claimed |
| EP-1155001-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 2001-11-21 | — | — | EP | claimed |
| WO-2000050406-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | LION BIOSCIENCE AG (DE) | 2000-08-31 | — | — | WO | claimed |
| EP-1155001-A4 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | LION BIOSCIENCE AG (DE) | 2003-05-28 | — | — | EP | disclosed |
| US-6417195-B1 | LIBRARIES AND COMBINATORIAL CHEMISTRY | LION BIOSCIENCE AG (DE) | 2002-07-09 | — | — | US | disclosed |
| EP-1155001-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000050406-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | LION BIOSCIENCE AG (DE) | 2000-08-31 | — | — | WO | disclosed |