Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011235 | 0.84 | SLC6A4 (0.84) | SLC6A4HTR1BHTR1ADRD1SLC6A2 | |
| SCHEMBL8383499 | 0.84 | SLC6A4 (0.51) | SLC6A4HTR1BHTR1AHTR1D | |
| SCHEMBL7003242 | 0.83 | SLC6A4 (0.57) | SLC6A4HTR1BHTR1AHTR1DCYP1A2 | |
| SCHEMBL6642008 | 0.82 | HTR1D (0.63) | SLC6A4HTR1BHTR1DCYP1A2CYP3A4 | |
| SCHEMBL6996942 | 0.82 | SLC6A4 (0.61) | SLC6A4IDO1HTR1BHTR1DCYP1A2 | |
| SCHEMBL8381443 | 0.82 | CYP1A2 (0.63) | SLC6A4HTR1BHTR1AHTR1DCYP1A2 | |
| SCHEMBL6995996 | 0.80 | SLC6A4 (0.59) | SLC6A4HTR1BHTR1DCYP1A2CYP3A4 | |
| SCHEMBL7014117 | 0.77 | SLC6A4 (0.56) | SLC6A4HTR1BHTR1AHTR1DCYP1A2 | |
| SCHEMBL7014120 | 0.77 | SLC6A4 (0.56) | SLC6A4HTR1BHTR1AHTR1DCYP1A2 | |
| SCHEMBL6997701 | 0.77 | HTR1D (0.57) | SLC6A4HTR1BHTR1AHTR1DCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114049-B1 | 3-BICYCLOINDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | NPS ALLELIX CORP (CA) | 2003-03-19 | — | — | EP | claimed |
| EP-1114049-B1 | 3-BICYCLOINDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | NPS ALLELIX CORP (CA) | 2003-03-19 | — | — | EP | disclosed |