SCHEMBL700269

SCHEMBL700269

Cc1ccc(/C=C/c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 6/20 0.61
MAOB P27338 2/20 0.56
CYP19A1 P11511 1/20 0.56
MAOA P21397 1/20 0.56
RELA Q04206 2/20 0.56
TRPA1 O75762 1/20 0.56
CYP1B1 Q16678 1/20 0.55
ALDH1A1 P00352 1/20 0.55
CYP3A4 P08684 1/20 0.55
MAPT P10636 1/20 0.55
HPGD P15428 1/20 0.55
FGF23 Q9GZV9 1/20 0.53
LMNA P02545 1/20 0.53
TSHR P16473 1/20 0.53
ALOX12 P18054 1/20 0.53
ACHE P22303 1/20 0.53
CHAT P28329 1/20 0.52
ALOX5 P09917 2/20 0.52
PTGS1 P23219 2/20 0.52
PTGS2 P35354 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4585867 1.00 NFE2L2 (0.61) NFE2L2MAOBCYP19A1MAOARELA
SCHEMBL840358 1.00 NFE2L2 (0.61) NFE2L2MAOBCYP19A1MAOARELA
SCHEMBL1239547 1.00 NFE2L2 (0.61) NFE2L2MAOBCYP19A1MAOARELA
SCHEMBL7164327 1.00 NFE2L2 (0.61) NFE2L2MAOBCYP19A1MAOARELA
SCHEMBL4585865 1.00 NFE2L2 (0.61) NFE2L2MAOBCYP19A1MAOARELA
SCHEMBL4585859 1.00 NFE2L2 (0.61) NFE2L2MAOBCYP19A1MAOARELA
(Z)-1,2-Diphenylethene SCHEMBL10630770 0.92 TSHR (0.65) NFE2L2MAOBCYP19A1MAOARELA
(Z)-1,2-Diphenylethene SCHEMBL10630776 0.92 TSHR (0.65) NFE2L2MAOBCYP19A1MAOARELA
SCHEMBL7164325 0.91 NFE2L2 (0.68) NFE2L2MAOBCYP19A1MAOARELA
SCHEMBL7164332 0.91 NFE2L2 (0.68) NFE2L2MAOBCYP19A1MAOARELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117402026-A Molecular isomerization method based on perovskite nanocrystalline sensitization 中国科学院大连化学物理研究所 2024-01-16 CN claimed
CN-116207442-A Core-shell material, composite diaphragm, preparation method of composite diaphragm and lithium ion battery 上海轩邑新能源发展有限公司 2023-06-02 CN claimed
CN-113355061-A External flexible internal rigid type oil-based drilling fluid nano plugging agent and oil-based drilling fluid 西南石油大学 2021-09-07 CN claimed
EP-2310446-B1 ACTIVATED HALO-CONTAINING ARALKYLSILANE MOMENTIVE PERFORMANCE MAT INC (US) 2015-12-23 EP claimed
CN-102177197-B Activated halo-containing aralkylsilane MOMENTIVE PERFORMANCE MAT INC 2013-11-06 CN claimed
US-8143336-B2 Activated halo-containing aralkylsilane composition, process of preparing same and rubber compositions made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-27 US claimed
CN-102177197-A Activated halo-containing aralkylsilane MOMENTIVE PERFORMANCE MAT INC 2011-09-07 CN claimed
EP-2310446-A1 ACTIVATED HALO-CONTAINING ARALKYLSILANE Momentive Performance Materials Inc. (US) 2011-04-20 EP claimed
WO-2010017370-A1 ACTIVATED HALO-CONTAINING ARALKYLSILANE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-02-11 WO claimed
US-20100036018-A1 ACTIVATED HALO-CONTAINING ARALKYLSILANE COMPOSITION, PROCESS OF PREPARING SAME AND RUBBER COMPOSITIONS MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2010-02-11 US claimed
US-12404221-B2 Methods of arene alkenylation UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2025-09-02 US disclosed
WO-2025094946-A1 ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF, KIT FOR TREATMENT OF CANCER, AND COMPOSITION FOR TREATMENT OF CANCER 国立大学法人東海国立大学機構 2025-05-08 WO disclosed
WO-2025063197-A1 CRYSTAL, METHOD FOR PRODUCING CRYSTAL, AND METHOD FOR INDUCING SELF-ORGANIZATION OF SILANOL COMPOUND 国立研究開発法人産業技術総合研究所 2025-03-27 WO disclosed
CN-113195801-B Crystal, method for producing crystal, and method for self-assembling silanol compound 国立研究开发法人产业技术综合研究所 2024-10-15 CN disclosed
CN-117402026-A Molecular isomerization method based on perovskite nanocrystalline sensitization 中国科学院大连化学物理研究所 2024-01-16 CN disclosed
EP-0041043-A1 Process for the preparation of derivatives of alkenyl benzene or alkenyl naphthalene CIBA-GEIGY AG (CH) 1981-12-02 EP disclosed
US-4216105-A Compositions for the optical whitening of organic materials and use thereof HICKSON & WELCH LIMITED (GB) 1980-08-05 US disclosed
US-4158099-A FROM SCHIFF BASES AND BIPHENYL COMPOUND CIBA-GEIGY AG (CH) 1979-06-12 US disclosed
US-4153719-A Aromatic diketones STERLING DRUG INC. (US) 1979-05-08 US disclosed
US-3991049-A Aromatic compounds containing ethylene double bonds, processes for their manufacture and use CIBA-GEIGY AG (CH) 1976-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404221-B2 Methods of arene alkenylation CYBB, CBR3, AHR NFE2L2 102/4885MAOB 157/4885CYP19A1 504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.