Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.38 |
| ▸ | CA2 | P00918 | 9/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004874 | 0.90 | PTGS2 (0.40) | PTGS2PTGS1 | |
| SCHEMBL7000770 | 0.89 | CA1 (0.37) | CA1CA2CA9CA12PTGS2 | |
| SCHEMBL6999948 | 0.88 | PTGS2 (0.43) | CA1CA2CA9CA12PTGS2 | |
| SCHEMBL7002714 | 0.83 | PTGS2 (0.39) | CA1CA2CA9CA12PTGS2 | |
| SCHEMBL6994981 | 0.80 | PTGS2 (0.39) | CA1CA2CA9CA12PTGS2 | |
| SCHEMBL6997162 | 0.80 | PTGS2 (0.40) | PTGS2PTGS1 | |
| SCHEMBL7003061 | 0.77 | PTGS2 (0.40) | PTGS2PTGS1 | |
| SCHEMBL7002267 | 0.76 | CA2 (0.54) | CA1CA2CA9CA12PTGS2 | |
| SCHEMBL6999156 | 0.75 | CA9 (0.49) | CA1CA2CA9CA12PTGS2 | |
| SCHEMBL6999688 | 0.75 | PTGS2 (0.60) | CA1CA2CA9CA12PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109799-B1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-12-17 | — | — | EP | claimed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | claimed |
| EP-1109799-B1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-12-17 | — | — | EP | disclosed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | disclosed |