Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 13/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7002898 | 1.00 | BMP1 (0.67) | BMP1MAPK1F2HPGDKMT2A | |
| SCHEMBL7004932 | 0.93 | BMP1 (0.66) | BMP1MAPK1F2HPGDKMT2A | |
| SCHEMBL6998726 | 0.82 | BMP1 (0.81) | BMP1 | |
| SCHEMBL23364658 | 0.81 | TAS2R14 (0.66) | MAPK1F2HPGDKMT2A | |
| SCHEMBL29932726 | 0.81 | TAS2R14 (0.66) | MAPK1F2HPGDKMT2A | |
| SCHEMBL6999599 | 0.78 | BMP1 (0.61) | BMP1 | |
| SCHEMBL7008077 | 0.76 | BMP1 (0.77) | BMP1 | |
| SCHEMBL31337093 | 0.75 | FFAR1 (0.56) | HPGDKMT2A | |
| SCHEMBL7008058 | 0.74 | BMP1 (1.00) | BMP1 | |
| SCHEMBL15267163 | 0.74 | SLC2A1 (0.56) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1154992-A4 | N-SUBSTITUTED ARYLSULFONYLAMINO HYDROXAMIC ACIDS USEFUL AS INHIBITORS OF C-PROTEINASE AND FOR TREATING OR PREVENTING DISORDERS RELATED TO UNREGULATED COLLAGEN PRODUCTION | FIBROGEN INC (US) | 2003-05-28 | — | — | EP | disclosed |
| EP-1154992-A1 | N-SUBSTITUTED ARYLSULFONYLAMINO HYDROXAMIC ACIDS USEFUL AS INHIBITORS OF C-PROTEINASE AND FOR TREATING OR PREVENTING DISORDERS RELATED TO UNREGULATED COLLAGEN PRODUCTION | FIBROGEN, INC. (US) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000050390-A1 | N-SUBSTITUTED ARYLSULFONYLAMINO HYDROXAMIC ACIDS USEFUL AS INHIBITORS OF C-PROTEINASE AND FOR TREATING OR PREVENTING DISORDERS RELATED TO UNREGULATED COLLAGEN PRODUCTION | FIBROGEN, INC. (US) | 2000-08-31 | — | — | WO | disclosed |