SCHEMBL7003134

SCHEMBL7003134

O=Cc1ccc2[nH]c3c4[nH]c5ccc(C=O)cc5c4c4c5cc(C=O)ccc5[nH]c4c3c2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.56
CYP2A6 P11509 2/20 0.42
CHEK1 O14757 4/20 0.40
ROCK2 O75116 3/20 0.39
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
AHR P35869 1/20 0.38
KMT2A Q03164 1/20 0.38
PIM1 P11309 2/20 0.38
PIM3 Q86V86 2/20 0.38
PDGFRB P09619 1/20 0.36
ALDH1A1 P00352 1/20 0.35
KDM4E B2RXH2 1/20 0.35
PTGS2 P35354 1/20 0.35
RAB9A P51151 1/20 0.35
PIM2 Q9P1W9 1/20 0.35
CCNB2 O95067 1/20 0.35
CCNE2 O96020 1/20 0.35
CDK1 P06493 1/20 0.35
CDK4 P11802 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6299735 0.80 KIF11 (0.81) KIF11CYP2A6MEN1MAPTAHR
Benzene SCHEMBL28184721 0.76 KIF11 (0.81) KIF11CYP2A6MEN1MAPTAHR
SCHEMBL28184723 0.74 KIF11 (0.56) KIF11CYP2A6MEN1MAPTAHR
SCHEMBL21563916 0.73 STING1 (0.53) CYP2A6ROCK2MEN1MAPTKMT2A
SCHEMBL11781048 0.72 KIF11 (0.42) KIF11CYP2A6CHEK1MEN1MAPT
SCHEMBL29823607 0.72 KIF11 (1.00) KIF11CYP2A6MEN1MAPTAHR
SCHEMBL8689823 0.72 KIF11 (0.68) KIF11CYP2A6MEN1MAPTAHR
SCHEMBL2775335 0.72 KIF11 (1.00) KIF11CYP2A6MEN1MAPTAHR
SCHEMBL27865132 0.71 SRC (0.58) KIF11CYP2A6PIM1PIM3ALDH1A1
SCHEMBL28106992 0.71 KIF11 (0.53) KIF11CYP2A6MEN1MAPTAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1327632-A1 METHOD FOR PRODUCING TRIMER OF INDOLE DERIVATIVE, AND TRIMER OF INDOLE DERIVATIVE AND LAMINATED STRUCTURE THEREOF Mitsubishi Rayon Co., Ltd. (JP) 2003-07-16 EP disclosed