SCHEMBL6299735

SCHEMBL6299735

O=Cc1ccc2[nH]c3ccc(C=O)cc3c2c1

nearest known ligand 0.81

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.81
CYP2A6 P11509 3/20 0.50
ALDH1A1 P00352 6/20 0.43
KDM4E B2RXH2 3/20 0.43
PTGS2 P35354 1/20 0.43
RAB9A P51151 1/20 0.43
HSD17B10 Q99714 4/20 0.40
MEN1 O00255 3/20 0.40
MAPT P10636 3/20 0.40
KMT2A Q03164 3/20 0.40
TSHR P16473 2/20 0.40
PIM1 P11309 1/20 0.40
PIM3 Q86V86 1/20 0.40
GFER P55789 1/20 0.40
HPGD P15428 1/20 0.39
AHR P35869 2/20 0.39
TDP1 Q9NUW8 1/20 0.38
ALDH5A1 P51649 1/20 0.37
ABAT P80404 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28184721 0.96 KIF11 (0.81) KIF11CYP2A6ALDH1A1KDM4EPTGS2
SCHEMBL2775335 0.90 KIF11 (1.00) KIF11CYP2A6ALDH1A1KDM4EHSD17B10
SCHEMBL29823607 0.90 KIF11 (1.00) KIF11CYP2A6ALDH1A1KDM4EHSD17B10
SCHEMBL8689823 0.90 KIF11 (0.68) KIF11CYP2A6ALDH1A1KDM4EPTGS2
SCHEMBL20006729 0.88 KIF11 (0.66) KIF11CYP2A6ALDH1A1KDM4ERAB9A
SCHEMBL18029477 0.88 KIF11 (0.66) KIF11CYP2A6ALDH1A1KDM4EMEN1
SCHEMBL29786741 0.84 ALDH1A1 (0.70) KIF11CYP2A6ALDH1A1KDM4ERAB9A
SCHEMBL15774556 0.84 KIF11 (0.65) KIF11ALDH1A1KDM4EMEN1KMT2A
SCHEMBL15774313 0.84 ALDH1A1 (0.70) KIF11CYP2A6ALDH1A1KDM4ERAB9A
SCHEMBL27865075 0.84 KIF11 (0.65) KIF11CYP2A6ALDH1A1KDM4EPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115991858-B Preparation method of high-temperature-resistant phenolic resin gel material 山东宇世巨化工有限公司 2023-06-02 CN claimed
CN-115991858-A Preparation method of high-temperature-resistant phenolic resin gel material 山东宇世巨化工有限公司 2023-04-21 CN claimed
JP-9295969-A None JP disclosed
US-20230285590-A1 POLYMER-CARGO-COMPLEXES COMPRISING CROSS-LINKED COPOLYMERS AND CARGO MOLECULES Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2023-09-14 US disclosed
US-20230285590-A1 POLYMER-CARGO-COMPLEXES COMPRISING CROSS-LINKED COPOLYMERS AND CARGO MOLECULES Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2023-09-14 US disclosed
CN-115991858-B Preparation method of high-temperature-resistant phenolic resin gel material 山东宇世巨化工有限公司 2023-06-02 CN disclosed
CN-115991858-A Preparation method of high-temperature-resistant phenolic resin gel material 山东宇世巨化工有限公司 2023-04-21 CN disclosed
US-20230021056-A1 METHOD OF PATTERNING LIGHT EMITTING LAYER, AND METHOD OF MANUFACTURING LIGHT-EMITTING DIODE DEVICE BOE TECHNOLOGY GROUP CO., LTD. (CN) 2023-01-19 US disclosed
WO-2021259783-A1 POLYMER-CARGO-COMPLEXES COMPRISING CROSS-LINKED COPOLYMERS AND CARGO MOLECULES Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2021-12-30 WO disclosed
EP-3928798-A1 POLYMER-CARGO-COMPLEXES COMPRISING CROSS-LINKED COPOLYMERS AND CARGO MOLECULES Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2021-12-29 EP disclosed
CN-105237462-B It is a kind of that there is high flatness diamine monomer and its synthetic method and application containing carbazole structure 湖南工业大学 2018-11-27 CN disclosed
US-20030203296-A1 Sulfonyldiphenylene-based charge transport compositions S-PRINTING SOLUTION CO., LTD. (KR) 2003-10-30 US disclosed
US-5736284-A HIGH SOLUBILITY IN POLYMER BINDER TAKASAGO INTERNATIONAL CORPORATION (JP) 1998-04-07 US disclosed
EP-0831813-A1 METHODS OF INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA AND COMPOUNDS USEFUL THEREFOR THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1998-04-01 EP disclosed
EP-0831811-A1 METHODS OF TREATING MICROBIAL INFECTIONS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1998-04-01 EP disclosed
JP-H09295969-A CARBAZOLE DERIVATIVE AND ELECTRIC-CHARGE TRANSFER MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR USING THE SAME TAKASAGO INTERNATL CORP 1997-11-18 JP disclosed
US-5668166-A CARBAZOLE COMPOUNDS GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 1997-09-16 US disclosed
US-5668167-A TREATMENT OF PNEUMOCYSTIS PNEUMONIA WITH CARBAZOLE DERIVATIVES DUKE UNIVERSITY (US) 1997-09-16 US disclosed
WO-1996040117-A1 METHODS OF TREATING MICROBIAL INFECTIONS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1996-12-19 WO disclosed
WO-1996040114-A1 METHODS OF INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA AND COMPOUNDS USEFUL THEREFOR THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1996-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230285590-A1 POLYMER-CARGO-COMPLEXES COMPRISING CROSS-LINKED COPOLYMERS AND CARGO MOLECULES KPNA6, EEA1, RAB5IF KIF11 217/4885CYP2A6 4825/4885ALDH1A1 4664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.