Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.49 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.48 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.47 |
| ▸ | ITK | Q08881 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24737951 | 1.00 | SLC9A1 (0.67) | SLC9A1HTR2AHTR2CHTR2BFFAR1 | |
| SCHEMBL10288769 | 1.00 | SLC9A1 (0.67) | SLC9A1HTR2AHTR2CHTR2BFFAR1 | |
| SCHEMBL7003208 | 1.00 | SLC9A1 (0.67) | SLC9A1HTR2AHTR2CHTR2BFFAR1 | |
| SCHEMBL21501023 | 1.00 | SLC9A1 (0.67) | SLC9A1HTR2AHTR2CHTR2BFFAR1 | |
| SCHEMBL1207144 | 1.00 | SLC9A1 (0.67) | SLC9A1HTR2AHTR2CHTR2BFFAR1 | |
| SCHEMBL8357586 | 0.88 | SLC9A1 (0.67) | SLC9A1HTR2AHTR2CHTR2BGPR88 | |
| SCHEMBL30997748 | 0.86 | SLC9A1 (0.73) | SLC9A1HTR2AHTR2CHTR2BGPR88 | |
| SCHEMBL7006240 | 0.84 | FFAR1 (0.62) | SLC9A1FFAR1 | |
| SCHEMBL9385280 | 0.84 | FFAR1 (0.62) | SLC9A1FFAR1 | |
| SCHEMBL6326088 | 0.84 | SLC9A1 (0.62) | SLC9A1HTR2AHTR2CHTR2BFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996621-B1 | TRIAZOLO[4,5-d]PYRIMIDINE DERIVATIVES AS ANTI-THROMBOTIC AGENTS | ASTRAZENECA AB (SE) | 2003-10-01 | — | — | EP | disclosed |