Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257514 | 0.90 | MEN1 (0.57) | MEN1KMT2AMAPTHTTCYP1A2 | |
| SCHEMBL27725212 | 0.84 | KMT2A (0.62) | MEN1KMT2AMAPTHTTCYP1A2 | |
| SCHEMBL3307725 | 0.84 | KMT2A (0.64) | MEN1KMT2AMAPTHTTCYP1A2 | |
| SCHEMBL5182303 | 0.83 | LMNA (0.69) | MEN1KMT2AMAPTHTTRECQL | |
| SCHEMBL8876963 | 0.83 | KMT2A (0.63) | MEN1KMT2AMAPTHTTCYP1A2 | |
| SCHEMBL3801020 | 0.82 | KMT2A (0.63) | MEN1KMT2AMAPTHTTCYP1A2 | |
| SCHEMBL3341413 | 0.82 | LMNA (0.53) | MEN1KMT2AMAPTHTTRECQL | |
| SCHEMBL31480868 | 0.81 | ALDH1A1 (0.69) | MEN1KMT2AMAPTHTTCYP3A4 | |
| SCHEMBL8723961 | 0.81 | KMT2A (0.60) | MEN1KMT2AMAPTHTTCYP1A2 | |
| SCHEMBL2337052 | 0.81 | KMT2A (0.67) | MEN1KMT2AMAPTHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1166623-C | 2-phenoxyaniline derivatives | ������ҩ��ʽ���� | 2004-09-15 | — | — | CN | disclosed |
| EP-1252163-B1 | 4-PYRIDYL-AND 2,4-PYRIMIDINYL-SUBSTITUTED PYRROLE DERIVATIVES AND THEIR USE IN PHARMACY | MERCKLE GMBH (DE) | 2003-09-24 | — | — | EP | disclosed |
| EP-0978506-B1 | 2-PHENOXYANILINE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-6156801-A | 2-phenoxyaniline derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2000-12-05 | — | — | US | disclosed |
| CN-1251571-A | 2-phenoxyaniline derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2000-04-26 | — | — | CN | disclosed |
| EP-0978506-A1 | 2-PHENOXYANILINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2000-02-09 | — | — | EP | disclosed |