Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 18/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5768503 | 0.89 | GRM6 (0.37) | KEAP1NFE2L2ADORA1KMT2A | |
| SCHEMBL5769847 | 0.89 | GRM6 (0.37) | KEAP1NFE2L2ADORA1KMT2A | |
| SCHEMBL5768500 | 0.89 | GRM6 (0.37) | KEAP1NFE2L2ADORA1KMT2A | |
| SCHEMBL5838542 | 0.85 | ADORA1 (0.43) | ADORA1KMT2A | |
| SCHEMBL6999013 | 0.85 | ADORA1 (0.43) | ADORA1KMT2A | |
| SCHEMBL7490590 | 0.82 | KEAP1 (0.45) | KEAP1NFE2L2ADORA1ATML3MBTL1 | |
| SCHEMBL7094861 | 0.78 | ADORA1 (0.40) | ADORA1KMT2A | |
| SCHEMBL7094863 | 0.78 | ADORA1 (0.40) | ADORA1KMT2A | |
| SCHEMBL5768050 | 0.74 | GRM6 (0.41) | ADORA1KMT2A | |
| SCHEMBL7560915 | 0.74 | GRM6 (0.41) | ADORA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301516-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2003-04-16 | — | — | EP | disclosed |