Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | WDR5 | P61964 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3873090 | 0.85 | MAPK1 (0.56) | MAPK1LMNARAB9AS1PR3WDR5 | |
| SCHEMBL7003317 | 0.84 | LMNA (0.56) | MAPK1LMNARAB9AS1PR3WDR5 | |
| SCHEMBL18891249 | 0.82 | MAPK1 (0.59) | MAPK1LMNARAB9AS1PR3WDR5 | |
| SCHEMBL7433558 | 0.82 | S1PR3 (0.53) | MAPK1LMNARAB9AS1PR3WDR5 | |
| SCHEMBL29017033 | 0.80 | S1PR3 (0.57) | MAPK1LMNARAB9AS1PR3WDR5 | |
| SCHEMBL2574654 | 0.80 | S1PR3 (0.57) | MAPK1LMNARAB9AS1PR3WDR5 | |
| SCHEMBL4268302 | 0.79 | S1PR3 (0.56) | MAPK1LMNARAB9AS1PR3WDR5 | |
| SCHEMBL30823666 | 0.79 | S1PR3 (0.56) | MAPK1LMNARAB9AS1PR3WDR5 | |
| SCHEMBL5038152 | 0.79 | S1PR3 (0.56) | MAPK1LMNARAB9AS1PR3WDR5 | |
| SCHEMBL4601864 | 0.73 | PTPN11 (0.52) | MAPK1LMNARAB9AS1PR3WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129093-B1 | PYRAZOLOPYRIMIDINONE DERIVATIVES FOR THE TREATMENT OF IMPOTENCE | DONG A PHARM CO LTD (KR) | 2003-07-23 | — | — | EP | disclosed |
| US-6583147-B1 | 5-(2-ethoxy-5-(isopropylamidosulfonyl)phenyl)-1-methyl-3-propy l- 1,6-dihydro-7H-pyrazolo(4,3-d)pyrimidin-7-one; | DONG A PHARM CO., LTD. (KR) | 2003-06-24 | — | — | US | disclosed |