Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | WDR5 | P61964 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3873090 | 0.85 | MAPK1 (0.56) | S1PR3MAPK1LMNARAB9AKDM4E | |
| SCHEMBL18891249 | 0.82 | MAPK1 (0.59) | S1PR3MAPK1LMNARAB9AWDR5 | |
| SCHEMBL7003785 | 0.82 | MAPK1 (0.53) | S1PR3MAPK1LMNARAB9AKDM4E | |
| SCHEMBL29017033 | 0.80 | S1PR3 (0.57) | S1PR3MAPK1LMNARAB9AKDM4E | |
| SCHEMBL2574654 | 0.80 | S1PR3 (0.57) | S1PR3MAPK1LMNARAB9AKDM4E | |
| SCHEMBL5038152 | 0.79 | S1PR3 (0.56) | S1PR3MAPK1LMNARAB9ANPSR1 | |
| SCHEMBL30823666 | 0.79 | S1PR3 (0.56) | S1PR3MAPK1LMNARAB9AKDM4E | |
| SCHEMBL4268302 | 0.79 | S1PR3 (0.56) | S1PR3MAPK1LMNARAB9AKDM4E | |
| SCHEMBL3714577 | 0.79 | NPSR1 (0.51) | KDM4ENPSR1ALDH1A1GAA | |
| SCHEMBL7003317 | 0.79 | LMNA (0.56) | S1PR3MAPK1LMNARAB9AWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129093-A1 | PYRAZOLOPYRIMIDINONE DERIVATIVES FOR THE TREATMENT OF IMPOTENCE | Dong A Pharmaceutical Co. Ltd. (KR) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027848-A1 | PYRAZOLOPYRIMIDINONE DERIVATIVES FOR THE TREATMENT OF IMPOTENCE | DONG A PHARM. CO., LTD. (KR) | 2000-05-18 | — | — | WO | disclosed |