Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700753 | 0.89 | SRD5A2 (0.73) | SRD5A2HPGDNPC1RAB9AKDM4E | |
| SCHEMBL7005455 | 0.88 | SRD5A2 (0.59) | SRD5A2HPGDNPC1RAB9AKDM4E | |
| SCHEMBL7006504 | 0.85 | SRD5A2 (0.56) | SRD5A2HPGDNPC1RAB9AKDM4E | |
| SCHEMBL699482 | 0.84 | FLT3 (0.60) | HPGDNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL914178 | 0.82 | SRD5A2 (0.54) | SRD5A2HPGDNPC1RAB9AKDM4E | |
| SCHEMBL15099347 | 0.82 | KDM4E (0.49) | SRD5A2HPGDNPC1RAB9AKDM4E | |
| SCHEMBL7193910 | 0.80 | SRD5A1 (0.62) | SRD5A2HPGDNPC1RAB9AKDM4E | |
| SCHEMBL6595625 | 0.79 | SRD5A2 (0.77) | SRD5A2HPGDNPC1RAB9AKDM4E | |
| SCHEMBL914562 | 0.78 | KDM4E (0.52) | SRD5A2HPGDNPC1RAB9AKDM4E | |
| SCHEMBL914490 | 0.78 | KDM4E (0.54) | SRD5A2HPGDNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |