Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | RHEB | Q15382 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700753 | 0.90 | SRD5A2 (0.73) | SRD5A2ALOX5ATMALDH1A1HPGD | |
| SCHEMBL7004252 | 0.88 | SRD5A2 (0.58) | SRD5A2MMP2MMP1MMP9MMP12 | |
| SCHEMBL7006504 | 0.86 | SRD5A2 (0.56) | SRD5A2ALOX5MMP1MMP12ATM | |
| SCHEMBL914178 | 0.83 | SRD5A2 (0.54) | SRD5A2ALOX15MMP2ATMALDH1A1 | |
| SCHEMBL15099347 | 0.80 | KDM4E (0.49) | SRD5A2ALOX15MMP2MMP1MMP9 | |
| SCHEMBL699482 | 0.80 | FLT3 (0.60) | ATMALDH1A1HPGDKDM4ERAB9A | |
| SCHEMBL914490 | 0.79 | KDM4E (0.54) | SRD5A2ALOX15MMP2ATMALDH1A1 | |
| SCHEMBL916058 | 0.79 | SRD5A2 (0.49) | SRD5A2ALOX15ATMALDH1A1HPGD | |
| SCHEMBL8555912 | 0.78 | SRD5A2 (0.47) | SRD5A2ALOX15ALOX5MMP2ATM | |
| SCHEMBL4044123 | 0.78 | CDK1 (0.57) | ALOX15ALOX5MMP2ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |